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A new study published in JAMA Dermatology compared the efficacy of oral minoxidil with topical minoxidil in treating male hair loss (androgenetic alopecia).
The research, conducted as a double-blind, placebo-controlled randomised trial, involved dividing participants into two groups: one group received 5mg of oral minoxidil daily, while the other used 5% topical minoxidil twice a day for a period of 24 weeks.
The study results showed no significant difference in hair density between the two groups, indicating that both treatments demonstrated comparable levels of improvement in hairline and vertex hair density. However, the group that used oral minoxidil had higher rates of hypertrichosis (excessive hair growth) and headache.
According to the study authors, oral minoxidil is well-tolerated but does not demonstrate superiority over topical minoxidil in treating male patients with androgenetic alopecia.
What does this mean?
The study suggests that for men with androgenetic alopecia, topical minoxidil treatment may be an equally effective option with fewer side effects compared to oral minoxidil. It is important to note that these results do not invalidate the efficacy of minoxidil as a treatment, but rather compare the two methods of application.
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